Pharmaceutical composition for treating peptic ulcer and its preparation method and use

一种治疗消化性溃疡的药物组合物及其制备方法和应用

Abstract

本发明提供了一种治疗消化性溃疡的药物组合物及其制备方法和应用,所述的药物组合物组成成分及其含量按重量份计包括:腺苷1~10份、精氨酸10~35份、多巴胺1~10份、色氨酸1~10份、谷氨酰胺6~25份、苏氨酸8~35份、甲硫氨酸6~25份、丝氨酸6~25份、脯氨酸8~35份、环(甘-脯)二肽1~10份。所述的药物组合物可以是任何适合服用的药物剂型,优选液体制剂、片剂、胶囊剂。本发明所述的药物组合物对大鼠胃溃疡模型的溃疡抑制率能达到71%,对消化性溃疡治疗总有效率能达到96%,且痊愈后复发几率小。
The invention provides a pharmaceutical composition for treating peptic ulcer and its preparation method and use. The pharmaceutical composition comprises, by weight, 1-10 parts of adenosine, 10-35 parts of arginine, 1-10 parts of dopamine, 1-10 parts of tryptophan, 6-25 parts of glutamine, 8-35 parts of threonine, 6-25 parts of methionine, 6-25 parts of serine, 8-35 parts of proline and 1-10 parts of cyclo(glycine-proline)dipeptide. The pharmaceutical composition can be processed to form any dosage forms suitable for eating and preferably to form a liquid preparation, a tablet or a capsule. The pharmaceutical composition has a rat peptic ulcer model ulcer inhibition ratio of 71%. The pharmaceutical composition has the peptic ulcer treatment total effective rate of 96% and a low recurrence rate after cure.

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