一种超润滑血清白蛋白泪点塞及其制备方法

Super-lubricating serum albumin punctal plug and preparation method thereof

Abstract

The invention discloses a super-lubricating serum albumin punctal plug and a preparation method of the super-lubricating serum albumin punctal plug. The punctal plug provided by the invention is provided with a main body (2), a first section (1), a second section (3) and a super-lubricating coating (4). After the super-lubricating serum albumin punctal plug is soaked by a hydrophilic polymer solution, a hydrophilic macromolecular coating is formed on the surface of the serum albumin punctal plug through chemical reaction, when the hydrophilic macromolecular coating contacts water, hydrophilic groups of the water-soluble polymers are combined with water and rapidly swell, the lubricating property is good, thus the injury caused to the soft tissue when the punctal plug is implanted is reduced, the pain is alleviated, the occurrence of complications is prevented, and therefore, the super-lubricating serum albumin punctal plug is particularly suitable for the clinical application.
本发明公开了一种超润滑血清白蛋白泪点塞。本发明所述泪点塞具有主体(2)、第一节段(1)第二节段(3)和超润滑涂层(4)。血清白蛋白泪点塞表面在亲水性聚合物溶液浸泡后通过化学反应形成亲水性的高分子涂层,当与水接触时,水溶性高分子的亲水基团与水结合迅速溶涨,具有优良的润滑性能,可减少了泪点塞植入时对软组织的损伤,减轻疼痛,防止了并发症的发生,因而更适合于临床应用。

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